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Fenbendazole

MechanismPLAUSIBLEOutcomeD
Claimed

A dog dewormer that kills cancer cells through microtubule disruption, p53 and several other pathways, made famous by a rancher's stage 4 lung cancer story.

What holds up

Real mechanism list in cells and mice, cataloged in a 2024 review.

What it does not show

Poor human bioavailability. Famous case was also on trial immunotherapy so cannot be credited to fenbendazole.

Evidence for

Nguyen et al., Anticancer Research 2024;44(9):3725, Yamaguchi et al., Clinical Case Reports 2016

Sources

VERIFIED Nguyen et al., Anticancer Research 2024;44(9):3725. VERIFIED Yamaguchi et al., Clinical Case Reports 2016. RETRACTED 'Stanford Fenbendazole Protocol': no such publication. RETRACTED 'University of Kentucky glioblastoma study': not found.

Grade history (append-only)

Every grade change is kept, never overwritten, so the current grade and every prior one stay visible.

Mechanism gradeJustificationGraded byStateGraded at
PLAUSIBLEReal mechanism list in cells and mice, cataloged in a 2024 review.seeddisplayed2026-09-03T21:29:06.027Z
Outcome gradeJustificationGraded byStateGraded at
DPoor human bioavailability. Famous case was also on trial immunotherapy so cannot be credited to fenbendazole.seeddisplayed2026-09-03T21:29:06.027Z

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