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Glutamine restriction and green tea (EGCG)

MechanismPLAUSIBLEOutcomeNONE
Claimed

Cutting glutamine starves the tumor's second fuel; EGCG from green tea blocks the enzyme glutamate dehydrogenase and so blocks glutamine use.

What holds up

Glutamine addiction is real, a live pharma target; EGCG inhibits glutamate dehydrogenase in cells.

What it does not show

No human trial has shown green tea, EGCG, or dietary glutamine restriction changes a cancer outcome.

Evidence for

Targeting glutamine metabolism as a potential target for cancer treatment, PMC 2025, An alternative mechanism of glutamate dehydrogenase inhibition by EGCG, PMC 2025, Targeting cancer hallmarks with EGCG, PMC 2024

Sources

PENDING Targeting glutamine metabolism as a potential target for cancer treatment, PMC 2025. PENDING An alternative mechanism of glutamate dehydrogenase inhibition by EGCG, PMC 2025. PENDING Targeting cancer hallmarks with EGCG, PMC 2024.

Grade history (append-only)

Every grade change is kept, never overwritten, so the current grade and every prior one stay visible.

Mechanism gradeJustificationGraded byStateGraded at
PLAUSIBLEGlutamine addiction is real, a live pharma target; EGCG inhibits glutamate dehydrogenase in cells.seeddisplayed2026-09-03T21:29:06.020Z
Outcome gradeJustificationGraded byStateGraded at
NONENo human trial has shown green tea, EGCG, or dietary glutamine restriction changes a cancer outcome.seeddisplayed2026-09-03T21:29:06.021Z

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